Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7946223 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL16714247 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10872158 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10695016 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL1009730 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL220293 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL9717471 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10966037 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL4319541 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL9304535 | 1.00 | DNM1 (0.68) | DNM1HTTSLC22A1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030029812-A1 | Mixtures of free halogen-generating biocides, halogen stabilizers and nitrogen containing biocides in water treatment and papermaking applications | LONZA INC. | 2003-02-13 | — | — | US | disclosed |
| US-6485790-B2 | BY ALSO APPLYING A WOOD DISTRIBUTION ENHANCING AGENT COMPRISING AMINE OXIDE(S) | LONZA INC. | 2002-11-26 | — | — | US | disclosed |
| US-20020061366-A1 | Methods for enhancing penetration of wood preservatives | LONZA INC. | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061366-A1 | Methods for enhancing penetration of wood preservatives | PNN, CD69, AKR1C2 | DNM1 4351/4885HTT 4396/4885SLC22A1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.