Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | AKT1 | P31749 | 2/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | CDC25A | P30304 | 1/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.58 |
| ▸ | FABP3 | P05413 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | PRKCG | P05129 | 2/20 | 0.50 |
| ▸ | PRKCB | P05771 | 2/20 | 0.50 |
| ▸ | PRKCA | P17252 | 2/20 | 0.50 |
| ▸ | PRKCH | P24723 | 2/20 | 0.50 |
| ▸ | PRKCI | P41743 | 2/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905581 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2693659 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL14447829 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL14447816 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL62054 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL14447974 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2695075 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL60426 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetradecylphosphocholine SCHEMBL1152910 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL5707895 | 1.00 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167408-A1 | NOVEL ALKYL PHOSPHOLIPID DERIVATIVES WITH REDUCED CYTOTOXICITY AND USES THEREOF | ZENTARIS GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| WO-2007071658-A2 | ALKYL PHOSPHOLIPID DERIVATIVES WITH REDUCED CYTOTOXICITY AND USES THEREOF | ÆTERNA ZENTARIS GMBH (DE) | 2007-06-28 | — | — | WO | disclosed |
| EP-1800684-A1 | Novel alkyl phospholipid derivatives and uses thereof | Zentaris GmbH (DE) | 2007-06-27 | — | — | EP | disclosed |
| US-6506393-B2 | Administering phosphocholine compound; leishmaniasis treatment | ZENTARIS AG (DE) | 2003-01-14 | — | — | US | disclosed |
| US-20010008885-A1 | Methods of treating protozoal diseases | MAX-PLANCK-GESSELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. | 2001-07-19 | — | — | US | disclosed |
| US-6254879-B1 | QUATERNARIUMAMINOETHYLPHOSPHATES | Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. (DE) | 2001-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008885-A1 | Methods of treating protozoal diseases | HRH2, HRH1, HRH4 | LMNA 1525/4885AKT1 2973/4885ESR1 4651/4885 |
| US-20070167408-A1 | NOVEL ALKYL PHOSPHOLIPID DERIVATIVES WITH REDUCED CYTOTOXICITY AND USES THEREOF | PHOSPHO1, PTDSS1, PTDSS2 | LMNA 2308/4885AKT1 1230/4885ESR1 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.