Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188063 | 0.95 | ESR1 (0.44) | ESR1ESR2ALDH2MAOAMAOB | |
| SCHEMBL7193207 | 0.94 | ESR1 (0.49) | ESR1ESR2ALDH2MAOAMAOB | |
| SCHEMBL7190011 | 0.92 | ESR1 (0.50) | ESR1ESR2ALDH2MAOAMAOB | |
| SCHEMBL7186036 | 0.91 | ESR1 (0.49) | ESR1ESR2ALDH2MAOAMAOB | |
| SCHEMBL7182784 | 0.89 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL7195159 | 0.89 | ESR1 (0.44) | ESR1ESR2ALDH2CYP4F2CYP4A11 | |
| SCHEMBL7181189 | 0.89 | ESR1 (0.52) | ESR1ESR2MAOBCYP4F2CYP4A11 | |
| SCHEMBL7193820 | 0.88 | ALOX5 (0.42) | ESR1ESR2ALDH2MAOACYP4F2 | |
| SCHEMBL7183659 | 0.87 | ESR1 (0.54) | ESR1ESR2ALDH2MAOAMAOB | |
| SCHEMBL7187993 | 0.85 | ESR1 (0.52) | ESR1ESR2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |