Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938193 | 0.82 | RAB9A (0.67) | HDAC1RAB9ANPC1HDAC3HDAC2 | |
| SCHEMBL221320 | 0.78 | HDAC3 (0.48) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL27736304 | 0.76 | HDAC3 (0.47) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL1810653 | 0.76 | RAB9A (0.47) | HDAC1RAB9ANPC1HDAC3HDAC2 | |
| SCHEMBL3172544 | 0.74 | NPSR1 (0.52) | MEN1KMT2AGAAPOLB | |
| SCHEMBL25002523 | 0.69 | HDAC3 (0.90) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL1937944 | 0.69 | HDAC3 (0.90) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL10400228 | 0.69 | RAB9A (0.67) | HDAC1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL1939168 | 0.69 | RAB9A (0.67) | HDAC1RAB9ANPC1HDAC3HDAC2 | |
| SCHEMBL14261156 | 0.68 | HDAC3 (0.87) | HDAC1HDAC3HDAC2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009451-B1 | COMPOSITIONS AND THEIR USE TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INST OF TECHN (US) | 2003-10-29 | — | — | EP | claimed |