Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938193 | 0.80 | RAB9A (0.67) | RAB9ANPC1HDAC1HDAC3HDAC2 | |
| SCHEMBL7188519 | 0.76 | HDAC1 (0.48) | RAB9ANPC1HDAC1HDAC3HDAC2 | |
| SCHEMBL13650005 | 0.75 | MAPT (0.61) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7866816 | 0.73 | RAB9A (0.47) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL8919802 | 0.73 | RAB9A (0.51) | RAB9ANPC1HDAC1HDAC3MEN1 | |
| SCHEMBL7866812 | 0.73 | RAB9A (0.47) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL16634476 | 0.72 | ALDH1A1 (0.47) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL16387330 | 0.72 | HDAC1 (0.55) | HDAC1HDAC3HDAC2MEN1KMT2A | |
| SCHEMBL23088816 | 0.70 | SNCA (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL29758188 | 0.70 | SNCA (0.43) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110119-B2 | Bi-functional co-polymer use for ophthalmic and other topical and local applications | CALM WATER THERAPEUTICS LLC (US) | 2021-09-07 | — | — | US | claimed |
| US-20200352984-A1 | Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications | CALM WATER THERAPEUTICS LLC | 2020-11-12 | — | — | US | claimed |
| US-10729715-B2 | Bi-functional co-polymer use for ophthalmic and other topical and local applications | EYEON PARTICLE SCIENCES LLC (US) | 2020-08-04 | — | — | US | claimed |
| US-20180161363-A1 | Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications | CALM WATER THERAPEUTICS LLC | 2018-06-14 | — | — | US | claimed |
| US-9884074-B2 | Bi-functional co-polymer use for ophthalmic and other topical and local applications | EYEON PARTICLE SCIENCES LLC (US) | 2018-02-06 | — | — | US | claimed |
| EP-3246048-A1 | BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS | Eyeon Particle Sciences LLC (US) | 2017-11-22 | — | — | EP | claimed |
| US-20160243156-A1 | Bi-Functional Co-Polymer Use for Ophthalmic and Other Topical and Local Applications | CALM WATER THERAPEUTICS LLC | 2016-08-25 | — | — | US | claimed |
| US-9283248-B2 | Bi-functional co-polymer use for ophthalmic and other topical and local applications | EYEON PARTICLE SCIENCES LLC (US) | 2016-03-15 | — | — | US | claimed |
| US-7029688-B2 | Methods and compositions to prevent formation of adhesions in biological tissues | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-18 | — | — | US | claimed |
| EP-1009451-B1 | COMPOSITIONS AND THEIR USE TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INST OF TECHN (US) | 2003-10-29 | — | — | EP | claimed |
| US-20030185787-A1 | Methods and compositions to prevent formation of adhesions in biological tissues | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-10-02 | — | — | US | claimed |
| US-6596267-B1 | Such as ethylene glycol-phenylboronic acid copolymer; prosthetics and implant coatings; readily adsorbs onto body tissues in situ providing steric barrier minimizing post-operative adhesion | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-07-22 | — | — | US | claimed |
| EP-1009451-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1999010022-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-03-04 | — | — | WO | claimed |
| US-20240117158-A1 | COMPOSITIONS AND METHODS FOR TREATING A DISORDER OR DEFECT IN SOFT TISSUE | UNIV DREXEL (US) | 2024-04-11 | — | — | US | disclosed |
| US-20230355661-A1 | BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS | CALM WATER THERAPEUTICS LLC | 2023-11-09 | — | — | US | disclosed |
| US-20220348745-A1 | Compositions and Methods for Treating a Disorder or Defect in Soft Tissue | UNIV DREXEL (US) | 2022-11-03 | — | — | US | disclosed |
| EP-1009451-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000012146-A1 | GELS AND MULTILAYER SURFACE STRUCTURES FROM BORONIC ACID CONTAINING POLYMERS | EIDGENÖSSISCH TECHNISCHE HOCHSCHULE ZURICH (CH) | 2000-03-09 | — | — | WO | disclosed |
| WO-1999010022-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185787-A1 | Methods and compositions to prevent formation of adhesions in biological tissues | ITGB6, ITGA6, EPCAM | RAB9A 1365/4885NPC1 3864/4885HDAC1 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.