SCHEMBL7188784

SCHEMBL7188784

N#CSc1cccc([O])c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MAPT P10636 5/20 0.42
POLB P06746 1/20 0.42
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
GFER P55789 1/20 0.35
HTT P42858 1/20 0.33
FTO Q9C0B1 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA2 P47869 1/20 0.33
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28183847 0.84 ALDH1A1 (0.44) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL3392990 0.74 ACHE (0.46) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL6245615 0.74 KMT2A (0.39) ALDH1A1MAPTPOLBGABRA1GABRG2
SCHEMBL31408760 0.74 CYP3A4 (0.46) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL11056267 0.74 CYP3A4 (0.46) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL23554066 0.74 DDB1 (0.45) ALDH1A1MAPTPOLBSMN1; SMN2
SCHEMBL14409994 0.74 ALDH1A1 (0.38) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL14257328 0.74 HAO1 (0.43) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL13764455 0.74 ALDH1A1 (0.38) ALDH1A1MAPTPOLBCA2CA5A
SCHEMBL26944302 0.74 MYC (0.43) ALDH1A1MAPTPOLBCA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6627714-B2 Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer MARUZEN PETROCHEMICAL CO., LTD. (JP) 2003-09-30 US disclosed
US-20020058767-A1 Method for producing an olefin type copolymer having a cyclic structure MARUZEN PETROCHEMICAL CO., LTD. (JP) 2002-05-16 US disclosed
EP-1205497-A2 Method for producing an olefin type copolymer having a cyclic structure MARUZEN PETROCHEMICAL CO., LTD. (JP) 2002-05-15 EP disclosed