Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747113 | 0.70 | ACLY (0.34) | ARG1ARG2MEN1LMNAKMT2A | |
| SCHEMBL487631 | 0.67 | MEN1 (0.54) | MEN1LMNAKMT2A | |
| SCHEMBL22149769 | 0.67 | — | — | |
| SCHEMBL1923397 | 0.67 | — | — | |
| SCHEMBL3406733 | 0.67 | TSHR (0.45) | — | |
| SCHEMBL28912850 | 0.65 | — | — | |
| SCHEMBL21038695 | 0.65 | — | — | |
| SCHEMBL11309980 | 0.65 | — | — | |
| Tromethamine SCHEMBL9235516 | 0.63 | LMNA (0.71) | ARG1ARG2MEN1LMNAKMT2A | |
| Tromethamine SCHEMBL8668436 | 0.63 | LMNA (0.71) | ARG1ARG2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350694-A | Composition method and device for measuring the divalent cation concentration or specific gravity of a test sample | MILES INC. (US) | 1994-09-27 | — | — | US | claimed |
| US-5320969-A | Measuring the change in color when complexing a metal compound and colored indicator in a buffered solution of biological sample, e.g. urine | MILES INC. (US) | 1994-06-14 | — | — | US | claimed |
| US-5302531-A | Mixture of complexing agent, metal compound and indicator | MILES INC. (US) | 1994-04-12 | — | — | US | claimed |
| US-5089420-A | With an indicator dye, a hydroperoxide and a buffer; especially useful for assaying accult blood | MILES INC. (US) | 1992-02-18 | — | — | US | claimed |
| EP-0230229-B1 | STABLE COMPOSITION FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCES | MILES INC. (US) | 1991-09-25 | — | — | EP | claimed |
| US-4755472-A | Stable composition for the determination of peroxidatively active substances | MILES INC. (US) | 1988-07-05 | — | — | US | claimed |
| EP-0230229-A2 | Stable composition for the determination of peroxidatively active substances | MILES INC. (US) | 1987-07-29 | — | — | EP | claimed |
| US-8609359-B2 | Methods for determining the concentration of gamma-hydroxy butyric acid (GHB) in a sample | BÜHLMANN LABORATORIES AG (CH) | 2013-12-17 | — | — | US | disclosed |
| US-20120052520-A1 | METHODS, COMPOSITIONS AND A KIT SUITABLE FOR DETERMINING THE CONCENTRATION OF GAMMA-HYDROXY BUTYRIC ACID (GHB) IN A SAMPLE | BUHLMANN LABORATORIES AG (CH) | 2012-03-01 | — | — | US | disclosed |
| EP-2253711-A1 | Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (GHB) in a sample | Bühlmann Laboratories AG (CH) | 2010-11-24 | — | — | EP | disclosed |
| WO-2010124999-A1 | METHODS, COMPOSITIONS AND A KIT SUITABLE FOR DETERMINING THE CONCENTRATION OF GAMMA-HYDROXY BUTYRIC ACID (GHB) IN A SAMPLE | BÜHLMANN LABORATORIES AG (CH) | 2010-11-04 | — | — | WO | disclosed |
| US-6703216-B2 | AN OXIDIZED COFACTOR FOR THE FIRST OXIDOREDUCTASE THAT IS REDUCED UPON OXIDATION OF GHB BY THE FIRST OXIDOREDUCTASE IS IN TURN OXIDIZED BY ANOTHER OXIDOREDUCTASE CAUSING DETECTABLE CONVERSION OF CHROMOGEN OR DYE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-03-09 | — | — | US | disclosed |
| US-20030175846-A1 | Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB) | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-09-18 | — | — | US | disclosed |
| EP-0444263-A1 | Improved composition, device and method of assaying for peroxidatively active substances | Bayer Corporation (US) | 1991-09-04 | — | — | EP | disclosed |
| EP-0444273-A1 | Composition, device and method of assaying for a peroxidatively active substance | MILES INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| EP-0238002-B1 | PROCESS FOR THE PREPARATION OF ALKENE CARBOXYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1989-07-19 | — | — | EP | disclosed |
| US-4755472-A | Stable composition for the determination of peroxidatively active substances | MILES INC. (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0266691-A2 | Method for the production of alkene carboxylic acid esters | BASF Aktiengesellschaft (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0238002-A1 | Process for the preparation of alkene carboxylic acids | BASF Aktiengesellschaft (DE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0230229-A2 | Stable composition for the determination of peroxidatively active substances | MILES INC. (US) | 1987-07-29 | — | — | EP | disclosed |