SCHEMBL7188934

SCHEMBL7188934

CCC1=C2c3c(-c4ccccc4)cccc3C1[Zr]C1C(CC)=C(c3c(-c4ccccc4)cccc31)[Si]2(C)C

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7189475 0.89 EDNRB (0.36) EDNRBEDNRA
SCHEMBL7187131 0.89 EDNRB (0.31) EDNRBEDNRA
SCHEMBL7194488 0.86 EDNRB (0.30) EDNRBEDNRA
SCHEMBL7187042 0.86 BRD4 (0.31)
SCHEMBL7188487 0.86 PARP1 (0.32)
SCHEMBL7189793 0.84 BRS3 (0.35)
SCHEMBL7193720 0.84
SCHEMBL7187654 0.83 HSD11B1 (0.35)
SCHEMBL1900079 0.83 PDCD1 (0.32) PDCD1CD274
SCHEMBL7194272 0.82 EDNRB (0.34) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583227-B2 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2003-06-24 US disclosed
US-20020160914-A1 Highly active supported catalyst compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-10-31 US disclosed
US-20010044506-A1 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2001-11-22 US disclosed