SCHEMBL7189475

SCHEMBL7189475

CCC1=C2c3c(-c4ccc(CC)cc4)cccc3C1[Zr]C1C(CC)=C(c3c(-c4ccc(CC)cc4)cccc31)[Si]2(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194272 0.93 EDNRB (0.34) EDNRBEDNRA
SCHEMBL7194488 0.91 EDNRB (0.30) EDNRBEDNRA
SCHEMBL7194232 0.91 EDNRB (0.33) EDNRBEDNRA
SCHEMBL7188847 0.90 EDNRB (0.36) EDNRBEDNRA
SCHEMBL7187131 0.90 EDNRB (0.31) EDNRBEDNRA
SCHEMBL7188934 0.89 EDNRB (0.30) EDNRBEDNRA
SCHEMBL7189793 0.89 BRS3 (0.35)
SCHEMBL7187645 0.89 EDNRB (0.32) EDNRBEDNRA
SCHEMBL7187654 0.88 HSD11B1 (0.35)
SCHEMBL7189785 0.87 HSD17B10 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP claimed