SCHEMBL7188959

SCHEMBL7188959

COc1cccc(OC)c1C(=O)Pc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
TAAR1 Q96RJ0 1/20 0.45
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CTSD P07339 1/20 0.42
KMT2A Q03164 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CA4 P22748 1/20 0.41
GAA P10253 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180680 0.89 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL7182735 0.89 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL7189098 0.86 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL7175420 0.85 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL7180207 0.85 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL7180557 0.84 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL7180453 0.83 ALDH1A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL7186783 0.83 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL7185189 0.83 KMT2A (0.47) CA12CA1CA2CA7CA9
SCHEMBL7177520 0.81 FABP4 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110121326-A Dental composition 登特斯普伊德特雷有限公司 2019-08-13 CN disclosed
CN-110022839-A Dental composition 登特斯普伊德特雷有限公司 2019-07-16 CN disclosed
CN-109996526-A Direct dental filled compositions 登特斯普伊德特雷有限公司 2019-07-09 CN disclosed
CN-109790245-A Method for preparing dental resin modified glass ionomer compositions 登特斯普伊德特雷有限公司 2019-05-21 CN disclosed
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed