Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195547 | 0.84 | TSHR (0.52) | TSHRMAPK1GAAGLAPOLB | |
| SCHEMBL7195566 | 0.84 | GAA (0.59) | TSHRMAPK1GAAGLAPOLB | |
| SCHEMBL7183524 | 0.83 | TSHR (0.47) | TSHRMAPK1GAAGLAPOLB | |
| SCHEMBL486844 | 0.82 | TSHR (0.52) | TSHRMAPK1GAACASP1CYP3A4 | |
| SCHEMBL27145615 | 0.81 | TSHR (0.47) | TSHRMAPK1GAAGLAPOLB | |
| SCHEMBL7194295 | 0.80 | TSHR (0.56) | TSHRMAPK1GAAGLAPOLB | |
| SCHEMBL7187852 | 0.79 | TSHR (0.55) | TSHRMAPK1GAAGLAPOLB | |
| SCHEMBL125232 | 0.78 | TSHR (0.60) | TSHRMAPK1CASP1CYP3A4RECQL | |
| SCHEMBL31476400 | 0.78 | TSHR (0.60) | TSHRMAPK1CASP1CYP3A4RECQL | |
| SCHEMBL29374282 | 0.78 | TSHR (0.60) | TSHRMAPK1CASP1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |