Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189999 | 0.94 | CYP4F2 (0.46) | CYP4F2CYP4A11MAPTLMNACYP1A2 | |
| SCHEMBL7195159 | 0.91 | ESR1 (0.44) | CYP4F2CYP4A11KDM4EFFAR1FFAR4 | |
| SCHEMBL7181142 | 0.91 | CYP4F2 (0.43) | CYP4F2CYP4A11MAPTLMNACYP1A2 | |
| SCHEMBL7193820 | 0.89 | ALOX5 (0.42) | CYP4F2CYP4A11MAPTLMNACYP1A2 | |
| SCHEMBL7183696 | 0.88 | FFAR1 (0.51) | MAPTLMNACYP1A2CYP3A4KDM4E | |
| SCHEMBL7194279 | 0.88 | CYP1A2 (0.47) | CYP4F2CYP4A11MAPTLMNACYP1A2 | |
| SCHEMBL7190395 | 0.85 | CYP1A2 (0.42) | CYP4F2CYP4A11MAPTLMNACYP1A2 | |
| SCHEMBL7194188 | 0.84 | ESR1 (0.45) | CYP4F2CYP4A11MAPTLMNACYP1A2 | |
| SCHEMBL7195351 | 0.84 | MAPT (0.47) | CYP4F2CYP4A11MAPTLMNAKDM4E | |
| SCHEMBL7193207 | 0.84 | ESR1 (0.49) | CYP4F2CYP4A11KDM4EMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |