Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 9/20 | 0.32 |
| ▸ | MAOA | P21397 | 8/20 | 0.32 |
| ▸ | KDM1A | O60341 | 6/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1741105 | 0.82 | MAOB (0.39) | MAOBMAOAKDM1A | |
| SCHEMBL5822879 | 0.73 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPK1ALDH1A1MEN1CYP2C9 | |
| SCHEMBL10477952 | 0.69 | TP53 (0.32) | SMN1; SMN2MAPK1MEN1KMT2ANFKB1 | |
| SCHEMBL20986946 | 0.68 | MAPK1 (0.41) | SMN1; SMN2MAPK1CHRM2CHRM4ALDH1A1 | |
| SCHEMBL6269153 | 0.67 | ALDH1A1 (0.36) | SMN1; SMN2MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11469864 | 0.66 | CFTR (0.39) | SMN1; SMN2MAPK1CHRM2CHRM4ALDH1A1 | |
| SCHEMBL16192645 | 0.66 | TP53 (0.30) | SMN1; SMN2MAPK1MEN1KMT2ANFKB1 | |
| SCHEMBL7187721 | 0.66 | TP53 (0.34) | SMN1; SMN2MAPK1MEN1KMT2ANFKB1 | |
| SCHEMBL11573985 | 0.66 | TP53 (0.30) | SMN1; SMN2MAPK1MEN1KMT2ANFKB1 | |
| SCHEMBL7182080 | 0.66 | TP53 (0.48) | SMN1; SMN2MAPK1MEN1KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |