SCHEMBL7189374

SCHEMBL7189374

CCCP(=O)(C(=O)c1c(Cl)cccc1Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.41
FEN1 P39748 1/20 0.38
ALDH1A1 P00352 2/20 0.38
F2R P25116 2/20 0.38
MAPT P10636 1/20 0.38
PTK2B Q14289 1/20 0.38
HPGD P15428 2/20 0.37
CFTR P13569 1/20 0.37
KMT2A Q03164 2/20 0.36
PLK1 P53350 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183540 0.92 TYK2 (0.40) L3MBTL1LMNAF2RMAPT
SCHEMBL7183600 0.91 TSHR (0.41) L3MBTL1LMNAFEN1HPGDKMT2A
SCHEMBL7177574 0.90 CETP (0.43) HPGDPLK1
SCHEMBL7180501 0.89 CETP (0.45) ALDH1A1MAPTHPGDPLK1
SCHEMBL7183523 0.89 CETP (0.45) ALDH1A1MAPTHPGDPLK1
SCHEMBL7175983 0.89 CETP (0.45) ALDH1A1MAPTHPGDPLK1
SCHEMBL7188223 0.89 CETP (0.45) ALDH1A1MAPTHPGDPLK1
SCHEMBL7186924 0.88 CA12 (0.42) L3MBTL1LMNAALDH1A1MAPTKMT2A
SCHEMBL7182200 0.88 ALDH1A1 (0.40) FEN1ALDH1A1F2RMAPTPTK2B
SCHEMBL7174866 0.84 ALDH1A1 (0.51) FEN1ALDH1A1MAPTPTK2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 L3MBTL1 126/4885LMNA 3247/4885FEN1 2512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.