SCHEMBL7182200

SCHEMBL7182200

CCP(=O)(C(=O)c1c(Cl)cccc1Cl)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
FEN1 P39748 1/20 0.40
MAPT P10636 1/20 0.39
PTK2B Q14289 1/20 0.39
HPGD P15428 1/20 0.37
USP2 O75604 1/20 0.37
AKR1B1 P15121 1/20 0.37
JAK2 O60674 1/20 0.36
JAK1 P23458 1/20 0.36
TYK2 P29597 1/20 0.36
F2R P25116 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
SMO Q99835 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182847 0.91 TYK2 (0.42) ALDH1A1MEN1GAAPKMTSHR
SCHEMBL7189374 0.88 L3MBTL1 (0.41) ALDH1A1MEN1KMT2AFEN1MAPT
SCHEMBL7188696 0.87 CA12 (0.44) ALDH1A1MEN1GAATSHRKMT2A
SCHEMBL7183600 0.85 TSHR (0.41) MEN1TSHRKMT2AFEN1HPGD
SCHEMBL7177574 0.84 CETP (0.43) TSHRHPGD
SCHEMBL7186440 0.83 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AFEN1MAPT
SCHEMBL7175983 0.83 CETP (0.45) ALDH1A1GAAMAPTHPGD
SCHEMBL7183523 0.83 CETP (0.45) ALDH1A1GAAMAPTHPGD
SCHEMBL7180501 0.83 CETP (0.45) ALDH1A1GAAMAPTHPGD
SCHEMBL7188223 0.83 CETP (0.45) ALDH1A1GAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ALDH1A1 3416/4885MEN1 2312/4885GAA 4753/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885MEN1 2263/4885GAA 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.