Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24762616 | 0.85 | LMNA (0.52) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL134991 | 0.81 | LMNA (0.56) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL30858931 | 0.81 | LMNA (0.56) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL1903216 | 0.81 | GRM5 (0.45) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL359708 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL3432856 | 0.78 | SYK (0.46) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL22923051 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL4341122 | 0.78 | LMNA (0.57) | SMN1; SMN2LMNAALDH1A1KDM4ETSHR | |
| SCHEMBL741038 | 0.78 | PARP10 (0.56) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL12320823 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579902-B1 | Antibiotic; ethoxy-carbamic acid 3'-ester of N-(7-((6-deoxy-5-C-methyl-4-O- methyl-alpha-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1 -benzopyran-3-yl)-benzeneacetamide | AVENTIS PHARMA S.A. (FR) | 2003-06-17 | — | — | US | disclosed |