Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065431 | 0.90 | HSP90AA1 (0.46) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL1160345 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL28069366 | 0.85 | MAPK1 (0.43) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL11579489 | 0.84 | ESR1 (0.50) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL8377448 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL6111894 | 0.82 | MAPK1 (0.35) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL10969248 | 0.82 | CNR1 (0.40) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL22320301 | 0.81 | MAPK1 (0.40) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL8395315 | 0.81 | CNR1 (0.38) | HSP90AA1ESR1ESR2AR | |
| SCHEMBL22320322 | 0.81 | TSHR (0.48) | SMN1; SMN2MAPK1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797938-B1 | METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN | BASF SE (DE) | 2016-06-01 | — | — | EP | disclosed |
| EP-2797938-A1 | METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN | BASF SE (DE) | 2014-11-05 | — | — | EP | disclosed |
| US-8841474-B2 | Process for preparing 6-chlorodibenzo[D,F][1,3,2]dioxaphosphepin | BASF SE (DE) | 2014-09-23 | — | — | US | disclosed |
| WO-2013098371-A1 | METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN | BASF SE (DE) | 2013-07-04 | — | — | WO | disclosed |
| US-20130172596-A1 | PROCESS FOR PREPARING 6-CHLORODIBENZO[D,F][1,3,2]DIOXAPHOSPHEPIN | BASF SE (DE) | 2013-07-04 | — | — | US | disclosed |
| US-6646148-B1 | Rapid, selective, efficient, stable | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-11 | — | — | US | disclosed |
| EP-0755302-B1 | BIDENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITIONS FOR HYDROCYANATION OF MONOOLEFINS | DU PONT (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5910600-A | Bisphosphite compound, process for its production and hydroformylation process employing the bisphosphite compound | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0755302-A1 | BIDENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITIONS FOR HYDROCYANATION OF MONOOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028228-A1 | BIDENTATE PHOSPHITE AND NICKEL CATALYST COMPOSITIONS FOR HYDROCYANATION OF MONOOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-10-26 | — | — | WO | disclosed |
| EP-0032681-B1 | HINDERED BIS-PHENOL PHENYL PHOSPHITES AND SYNTHETIC RESIN COMPOSITIONS HAVING ENHANCED STABILITY TO HEAT AND LIGHT | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4362830-A | Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
| EP-0032681-A2 | Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172596-A1 | PROCESS FOR PREPARING 6-CHLORODIBENZO[D,F][1,3,2]DIOXAPHOSPHEPIN | DCPS, PLCB3, DDT | SMN1; SMN2 4810/4885MAPK1 1022/4885NPC1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.