SCHEMBL28069366

SCHEMBL28069366

CCC(C)(C)c1cc(-c2ccccc2)c(O)c(C(C)(C)CC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
ATM Q13315 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
BACE1 P56817 2/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28249286 0.86 CNR1 (0.42) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL6111894 0.85 MAPK1 (0.35) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL7189472 0.85 SMN1; SMN2 (0.40) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL11759190 0.81 PTPN1 (0.56) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL1160345 0.79 SMN1; SMN2 (0.41) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL31510648 0.79 HNF4A (0.43) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL26632610 0.79 HNF4A (0.43) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL13840638 0.78 CA2 (0.47) SMN1; SMN2CYP1A2CYP3A4CYP2C9TSHR
SCHEMBL15457993 0.78 NPC1 (0.49) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL22320301 0.77 MAPK1 (0.40) MAPK1SMN1; SMN2NPC1LMNACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105518764-B The manufacturing method of optical component and ultraviolet-curing resin composition for the manufacturing method 日本化药株式会社 2019-11-08 CN disclosed
CN-108735651-A Cut die bonding film 日东电工株式会社 2018-11-02 CN disclosed
CN-108728003-A Cut die bonding film 日东电工株式会社 2018-11-02 CN disclosed
CN-108735650-A Cut die bonding film 日东电工株式会社 2018-11-02 CN disclosed
CN-108728000-A Cut die bonding film 日东电工株式会社 2018-11-02 CN disclosed
CN-107513293-A A kind of preparation method of caesium tungsten bronze modified powder and its slurry 广州市黑本新材料科技有限公司 2017-12-26 CN disclosed
CN-104204123-B Automotive hub protection bonding film 琳得科株式会社 2017-03-01 CN disclosed
CN-106244032-A A kind of EVA adhesive film used for solar batteries and preparation method thereof 上海天洋热熔粘接材料股份有限公司 2016-12-21 CN disclosed
CN-104629573-B The manufacture method of optical component and the application of the ultraviolet-curing resin composition for this manufacture method 日本化药株式会社 2016-09-14 CN disclosed
CN-103781878-B Cholesteric liquid-crystal mixture, film, selective reflecting plate, duplexer and laminated glass 富士胶片株式会社 2016-08-17 CN disclosed