Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144325 | 0.80 | NPC1 (1.00) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL1961388 | 0.79 | RAB9A (0.48) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL147377 | 0.78 | RAB9A (0.73) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL3503935 | 0.77 | NPC1 (0.67) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| Sulfuric Acid SCHEMBL28964142 | 0.75 | NPC1 (0.89) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL1567603 | 0.75 | RAB9A (0.74) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL1156914 | 0.75 | NPC1 (0.74) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL30603142 | 0.75 | NPC1 (0.68) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL8012168 | 0.74 | RAB9A (0.59) | RAB9ANPC1HTR2BHTR7CYP1A2 | |
| SCHEMBL27968688 | 0.74 | NPC1 (0.86) | RAB9ANPC1HTR2BCYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6593084-B2 | Carcinogen assay | Bird, Robert E. | 2003-07-15 | — | — | US | disclosed |
| US-20020086288-A1 | CARCINOGEN ASSAY | BIRD, ROBERT E. | 2002-07-04 | — | — | US | disclosed |
| EP-1121466-A1 | CARCINOGEN ASSAY | Bioreliance Testing and Development, Inc. (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000022168-A9 | CARCINOGEN ASSAY | MA BIOSERVICES INC (US) | 2000-09-14 | — | — | WO | disclosed |
| WO-2000022168-A1 | CARCINOGEN ASSAY | BIORELIANCE TESTING AND DEVELOPMENT, INC. (US) | 2000-04-20 | — | — | WO | disclosed |