SCHEMBL7189713

SCHEMBL7189713

Nc1ccc(S(=O)(=O)c2ccc(N)cc2Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.64
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
TSHR P16473 5/20 0.56
CYP3A4 P08684 5/20 0.56
HTR6 P50406 4/20 0.56
CYP2C9 P11712 2/20 0.56
LMNA P02545 1/20 0.56
MPO P05164 1/20 0.56
ALDH1A1 P00352 3/20 0.48
PKM P14618 1/20 0.48
THRB P10828 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HKDC1 Q2TB90 1/20 0.45
PRMT1 Q99873 1/20 0.44
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10972692 0.93 MEN1 (0.63) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL11214449 0.89 MEN1 (0.63) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL8866123 0.89 HSD11B1 (0.57) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL1300150 0.88 CYP3A4 (0.55) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL7185513 0.86 CYP3A4 (0.61) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL10921849 0.85 MEN1 (0.57) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL7191066 0.84 LMNA (0.63) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL7185389 0.82 HSD11B1 (0.51) HSD11B1MEN1KMT2ATSHRCYP3A4
SCHEMBL4368038 0.82 HSD11B1 (0.51) HSD11B1TSHRCYP3A4HTR6CYP2C9
SCHEMBL8867078 0.81 HSD11B1 (0.64) HSD11B1MEN1KMT2ATSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed