Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.59 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195835 | 1.00 | ADORA1 (0.59) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL5921422 | 0.85 | ADORA1 (0.47) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL2033894 | 0.83 | ADORA1 (0.60) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL10689183 | 0.81 | ADORA3 (0.73) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL8606410 | 0.81 | ADORA1 (0.64) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL8606022 | 0.81 | ADORA1 (0.64) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL8607675 | 0.81 | ADORA1 (0.64) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL8606939 | 0.81 | ADORA1 (0.64) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL7191539 | 0.81 | P2RY1 (0.60) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL120551 | 0.80 | ADORA3 (0.69) | ADORA1P2RY1SMN1; SMN2P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019426-B1 | NOVEL A1 ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS | UNIV FLORIDA (US) | 2003-03-12 | — | — | EP | claimed |
| EP-1019426-B1 | NOVEL A1 ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS | UNIV FLORIDA (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1019426-A1 | NOVEL A 1? ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS | THE UNIVERSITY OF FLORIDA (US) | 2000-07-19 | — | — | EP | disclosed |
| US-5736528-A | CARDIOTONIC AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1998-04-07 | — | — | US | disclosed |
| WO-1997024363-A1 | NOVEL A1 ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS | UNIVERSITY OF FLORIDA (US) | 1997-07-10 | — | — | WO | disclosed |