SCHEMBL7189792

SCHEMBL7189792

Cc1cc(N)cc(Oc2ccc(N)cc2)c1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.88
SMN1; SMN2 Q16637 3/20 0.88
TEAD4 Q15561 1/20 0.65
MAPT P10636 6/20 0.63
TDP1 Q9NUW8 3/20 0.63
POLB P06746 1/20 0.63
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
NPC1 O15118 3/20 0.60
RAB9A P51151 3/20 0.60
NLRP3 Q96P20 1/20 0.60
TSHR P16473 2/20 0.58
CYP3A4 P08684 1/20 0.58
MITF O75030 1/20 0.52
GAA P10253 1/20 0.52
GFER P55789 1/20 0.52
NLRP1 Q9C000 1/20 0.52
NOD2 Q9HC29 1/20 0.52
MAOA P21397 2/20 0.50
MAPK1 P28482 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17865520 0.94 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL19829397 0.91 ALDH1A1 (0.95) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL7188789 0.89 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL3653673 0.84 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL23759 0.84 MEN1 (0.79) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL20347020 0.84 ALDH1A1 (0.74) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9352887 0.84 ALDH1A1 (0.81) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL19697573 0.83 TEAD4 (0.86) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL17508240 0.82 NR4A1 (0.63) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9594721 0.82 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed