SCHEMBL7189830

SCHEMBL7189830

O=C(NO)c1c(O)ccc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 3/20 0.55
HDAC8 Q9BY41 2/20 0.55
MMP3 P08254 1/20 0.55
ALOX15 P16050 1/20 0.52
POLB P06746 1/20 0.50
PTPN22 Q9Y2R2 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
IDO1 P14902 1/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.46
ALDH1A1 P00352 1/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ERN1 O75460 1/20 0.46
MPO P05164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8358481 0.87 ALOX15 (0.54) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL1639535 0.84 ALOX15 (0.55) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL10822239 0.84 PLK1 (0.56) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL24953153 0.81 ALOX15 (0.56) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL6010476 0.81 ALOX15 (0.52) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL4971446 0.81 ALOX15 (0.67) ABCG2ALOX15MEN1KMT2AKDM4E
SCHEMBL29625679 0.81 ALOX15 (0.56) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL4139654 0.80 ABCG2 (0.57) ABCG2ALOX15POLBPTPN22MEN1
SCHEMBL9243226 0.80 KDM4E (0.50) ABCG2ALOX15PTPN22MEN1KMT2A
SCHEMBL13498479 0.80 MEN1 (0.50) ABCG2ALOX15MEN1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114058447-A Photocathode for photomultiplier and method for producing the same 杭州安誉科技有限公司 2022-02-18 CN claimed
CN-113512470-A Photocathode for photomultiplier and method for producing the same 杭州安誉科技有限公司 2021-10-19 CN claimed
JP-1242561-A None JP disclosed
CN-114058447-B Photocathode for photomultiplier and method for producing the same 杭州安誉科技有限公司 2022-07-01 CN disclosed
CN-114058447-A Photocathode for photomultiplier and method for producing the same 杭州安誉科技有限公司 2022-02-18 CN disclosed
CN-113512470-A Photocathode for photomultiplier and method for producing the same 杭州安誉科技有限公司 2021-10-19 CN disclosed
WO-2013059582-A2 SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES NUPOTENTIAL, INC. (US) 2013-04-25 WO disclosed
CN-1441637-A Compositions for repelling crawling insects BAYER AG (DE) 2003-09-10 CN disclosed
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed
JP-H01242561-A PRODUCTION OF AMINONAPHTHOLS FUJI PHOTO FILM CO LTD 1989-09-27 JP disclosed
EP-0127726-B1 HYDROXAMIC ACIDS, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS VEB Fahlberg-List Magdeburg (DD) 1987-08-26 EP disclosed
US-4670469-A ANTIASTHMATIC AGENTS; CARDIOVASCULAR DISORDERS VEB ARZNEIMITTELWERK DRESDEN (DD) 1987-06-02 US disclosed
EP-0127726-A1 Hydroxamic acids, their preparation and their use in pharmaceutical compositions VEB Fahlberg-List Magdeburg (DD) 1984-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 ABCG2 862/4885HDAC8 2741/4885MMP3 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.