SCHEMBL7190064

SCHEMBL7190064

Nc1ccc(Oc2ccc(N)cc2Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
ALDH1A1 P00352 8/20 0.52
TDP1 Q9NUW8 3/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MITF O75030 1/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
NLRP1 Q9C000 1/20 0.47
NOD2 Q9HC29 1/20 0.47
MAOA P21397 2/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TEAD4 Q15561 1/20 0.43
MAOB P27338 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20155306 0.89 MAOA (0.57) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL1471874 0.89 MEN1 (0.45) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL21904888 0.89 TDP1 (0.52) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL8914761 0.88 MAPT (0.50) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL5552580 0.88 MAOA (0.52) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL7186654 0.87 ALDH1A1 (0.58) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL31287768 0.85 MAOA (0.57) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL7195358 0.85 NR4A1 (0.41) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL15067954 0.84 FFAR1 (0.47) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL21652810 0.84 SLC6A4 (0.50) MAPTALDH1A1TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed