Methacrylic Acid

Methacrylic Acid

SCHEMBL7190474

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=O.C=O.CCCC=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
TSHR P16473 6/20 0.39
EP300 Q09472 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
FAAH O00519 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
ADH1B P00325 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL17710379 0.85 TSHR (0.39) ALDH1A1TSHRTDP1
Butanal SCHEMBL1521394 0.83
Butanal SCHEMBL10942938 0.82 ALDH1A1 (0.55) ALDH1A1TSHRFAAHTRPV1ADH1B
Methacrylic Acid SCHEMBL7785580 0.81 TSHR (0.44) ALDH1A1TSHREP300FAAHTRPV1
Glutaral SCHEMBL29520564 0.81 HIF1A (0.50) ALDH1A1TSHREP300FAAHTRPV1
Methacrylic Acid SCHEMBL3305565 0.81 TSHR (0.44) ALDH1A1TSHREP300FAAHTRPV1
Methacrylic Acid SCHEMBL10941131 0.80 ALDH1A1 (0.50) ALDH1A1TSHRGRIK1GRIK2TDP1
Butanal SCHEMBL5030019 0.80
Butanal SCHEMBL7474945 0.80
Butanal SCHEMBL1173336 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362893-A1 Thermoplastic elastomer resin composition Riken Technos Corporation (JP) 2003-11-19 EP disclosed
US-4892915-A Copolymers of 2-(2-hydroxy-5-acryloyloxyalkyl)phenyl-2H-benzotriazoles CIBA-GEIGY CORPORATION (US) 1990-01-09 US disclosed
US-4785063-A LIGHT STABILIZERS CIBA-GEIGY CORPORATION (US) 1988-11-15 US disclosed