SCHEMBL7190804

SCHEMBL7190804

CCCCc1ccc(C(=O)OO)c(C(=O)OO)c1CCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.39
CNR2 P34972 5/20 0.38
METAP2 P50579 1/20 0.38
PPARA Q07869 2/20 0.37
PPARG P37231 1/20 0.35
TSHR P16473 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 2/20 0.34
CYP3A4 P08684 2/20 0.34
MEN1 O00255 1/20 0.34
ALOX5 P09917 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPK1 P28482 1/20 0.34
CNR1 P21554 1/20 0.34
BID P55957 2/20 0.33
BCL2L1 Q07817 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28115840 0.94 PPARA (0.44) TYRPPARAPPARGTSHRTDP1
SCHEMBL7190798 0.91 METAP2 (0.41) TYRMETAP2PPARAPPARGMEN1
SCHEMBL7190813 0.91 PPARA (0.44) TYRCNR2METAP2PPARAPPARG
SCHEMBL8852377 0.88 PPARA (0.40) TYRCNR2METAP2PPARAPPARG
SCHEMBL1208160 0.88 TYR (0.41) TYRCNR2METAP2PPARATSHR
SCHEMBL28337063 0.85 ALDH1A1 (0.39) TYRCNR2PPARAL3MBTL1MEN1
SCHEMBL11688995 0.85 TSHR (0.46) CNR2TSHRTDP1L3MBTL1TP53
SCHEMBL8852388 0.82 PPARA (0.47) TYRMETAP2PPARAPPARGMAPT
SCHEMBL8852368 0.82 PPARA (0.44) TYRMETAP2PPARAPPARGMEN1
SCHEMBL21357020 0.82 TSHR (0.54) TSHRTDP1L3MBTL1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445837-B1 Crosslinkable polyester/isocyanate compositions suitable for the preparation of composite materials SIR IND SPA (IT) 1997-01-08 EP claimed
US-5382626-A Formation of polyurethanes and crosslinking with vinyl groups and unsaturated polyesters MONTEDISON S.P.A. (IT) 1995-01-17 US claimed
CN-118259564-A Toner and method for producing toner 佳能株式会社 2024-06-28 CN disclosed
US-6569936-B1 Rubber composition for a conveyor belt MITSUI CHEMICALS, INC. (JP) 2003-05-27 US disclosed
EP-0877053-B1 Rubber composition for a conveyor belt MITSUI CHEMICALS INC (JP) 2001-11-14 EP disclosed
EP-0877053-A2 Rubber composition for a conveyor belt Mitsui Chemicals, Inc. (JP) 1998-11-11 EP disclosed
EP-0445837-B1 Crosslinkable polyester/isocyanate compositions suitable for the preparation of composite materials SIR IND SPA (IT) 1997-01-08 EP disclosed
US-5382626-A Formation of polyurethanes and crosslinking with vinyl groups and unsaturated polyesters MONTEDISON S.P.A. (IT) 1995-01-17 US disclosed
EP-0445837-A2 Crosslinkable polyester/isocyanate compositions suitable for the preparation of composite materials Montedison S.p.A. (IT) 1991-09-11 EP disclosed