Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.60 |
| ▸ | TYMP | P19971 | 4/20 | 0.50 |
| ▸ | PYGM | P11217 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445235 | 1.00 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL7190817 | 1.00 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL3445234 | 1.00 | TK2 (0.60) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL6535173 | 0.89 | TK2 (0.60) | TK2TYMPPYGM | |
| SCHEMBL7712041 | 0.89 | TK2 (0.60) | TK2TYMPPYGM | |
| SCHEMBL24229243 | 0.87 | TK2 (0.67) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL5502493 | 0.87 | TK2 (0.67) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL6512561 | 0.87 | TK2 (0.64) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL10267691 | 0.87 | TK2 (0.67) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL5502489 | 0.87 | TK2 (0.67) | TK2TYMPPYGMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586184-B2 | Rearranging target nucleotide sequences; obtain cells, transfor with nucleotide sequences, detecting nucleotide sequences adjustment in prokaryotic cell | VALIGEN (U.S.), INC. | 2003-07-01 | — | — | US | claimed |
| US-20020151072-A1 | Chimeric mutational vectors | VALIGEN (U.S), INC. | 2002-10-17 | — | — | US | claimed |
| EP-1078097-A4 | CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS | KIMERAGEN INC (US) | 2002-06-05 | — | — | EP | claimed |
| EP-1084272-A4 | HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA | KIMERAGEN INC (US) | 2002-03-13 | — | — | EP | claimed |
| US-6211351-B1 | FOR INTRODUCTION OF GENETIC CHANGES IN EUKARYOTIC CELLS | VALIGEN (US), INC. | 2001-04-03 | — | — | US | claimed |
| EP-1084272-A1 | HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA | Kimeragen Inc. (US) | 2001-03-21 | — | — | EP | claimed |
| EP-1078097-A1 | CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS | Kimeragen Inc. (US) | 2001-02-28 | — | — | EP | claimed |
| US-6010907-A | TRANSFORMING TARGET DNA SEQUENCES | KIMERAGEN, INC. (US) | 2000-01-04 | — | — | US | claimed |
| US-6004804-A | 3'-EXONUCLEASE PROTECTED DUPLEX MUTATIONAL VECTORS; USED TO MAKE SPECIFIC GENETIC ALTERATIONS IN THE GENOME AND IN PLASMIDS OF TARGET PROKARYOTIC CELLS | KIMERAGEN, INC. (US) | 1999-12-21 | — | — | US | claimed |
| WO-1999058702-A1 | CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS | KIMERAGEN, INC. (US) | 1999-11-18 | — | — | WO | claimed |
| WO-1999058723-A1 | HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA | KIMERAGEN, INC. (US) | 1999-11-18 | — | — | WO | claimed |
| EP-0866865-B1 | CHIMERIC OLIGOMERS HAVING AN RNA-CLEAVAGE ACTIVITY | VIMRX HOLDINGS LTD (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0866865-A1 | CHIMERIC OLIGOMERS HAVING AN RNA-CLEAVAGE ACTIVITY | Vimrx Holdings, Ltd. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997018312-A9 | CHIMERIC OLIGOMERS HAVING AN RNA-CLEAVAGE ACTIVITY | — | 1998-08-13 | — | — | WO | disclosed |
| WO-1997018312-A1 | CHIMERIC OLIGOMERS HAVING AN RNA-CLEAVAGE ACTIVITY | VIMRX HOLDINGS, LTD. (US) | 1997-05-22 | — | — | WO | disclosed |