Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14797416 | 0.84 | KMT2A (0.61) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL27568071 | 0.77 | SCN4A (0.61) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL1385879 | 0.74 | SCN4A (0.55) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL27774356 | 0.72 | CYP19A1 (0.54) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL29095278 | 0.71 | SCN4A (0.48) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL3365533 | 0.71 | SCN4A (0.69) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL1384820 | 0.71 | SCN4A (1.00) | SCN4ANPC1RAB9ACA1CA2 | |
| SCHEMBL27007450 | 0.71 | SCN4A (0.55) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL7048807 | 0.71 | SCN4A (0.51) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL28057077 | 0.71 | SCN4A (0.51) | SCN4AKMT2ANPC1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589997-B2 | 1-Phenylprop-2-en-1-one derivatives as wound healing, anticarcinogenic, antiarthritic, antitumor, antiproliferative, antiinflammatory or antimetastasis agents | NORTH SHORE-LONG ISLAND JEWISH HEALTH SYSTEM | 2003-07-08 | — | — | US | disclosed |