Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.51 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15072164 | 0.86 | KMT2A (0.50) | KMT2AKDM4EALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL2148390 | 0.82 | ALDH1A1 (0.46) | KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27743341 | 0.78 | GRM5 (0.52) | SCN4ATNK2CA1CA2NPC1 | |
| SCHEMBL12857463 | 0.77 | ABCB11 (0.58) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL27764186 | 0.77 | FYN (0.50) | SCN4ATNK2CA1CA2NPC1 | |
| SCHEMBL218118 | 0.75 | KMT2A (0.57) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL4316115 | 0.74 | ABCB11 (0.55) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10418488 | 0.73 | KMT2A (0.55) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL27568071 | 0.73 | SCN4A (0.61) | SCN4ACA1CA2NPC1RAB9A | |
| SCHEMBL7011494 | 0.73 | NOTUM (0.61) | SCN4ATNK2NPC1RAB9ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101426792-A | Pyrazolopyrimidines as therapeutic agents | ABBOTT GMBH & CO KG (DE) | 2009-05-06 | — | — | CN | disclosed |
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |