Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733155 | 0.83 | AKR1B10 (0.56) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL7192466 | 0.79 | AKR1B10 (0.53) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL14139155 | 0.79 | HTT (0.60) | AKR1B10AKR1B1AKR1C3MEN1KMT2A | |
| SCHEMBL4117028 | 0.76 | HTT (0.67) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL2492351 | 0.76 | AKR1B10 (0.58) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL5165720 | 0.76 | AKR1B10 (0.54) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL30199523 | 0.76 | AKR1B10 (0.63) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL5166422 | 0.73 | AKR1B10 (0.51) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL29486322 | 0.73 | HTT (0.48) | AKR1B10AKR1B1AKR1C3MMP2PAK1 | |
| SCHEMBL5774375 | 0.72 | MEN1 (0.47) | AKR1B10AKR1B1AKR1C3MMP2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065229-A1 | Phenol derivatives, process for preparation of the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1184362-A1 | PHENOL DERIVATIVES, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2002-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065229-A1 | Phenol derivatives, process for preparation of the same and use thereof | ACR, SHARPIN, AGPS | AKR1B10 851/4885AKR1B1 1008/4885AKR1C3 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.