SCHEMBL7192004

SCHEMBL7192004

CCc1ccccc1C(Cl)(Cl)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
CYP1A2 P05177 1/20 0.41
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
POLQ O75417 1/20 0.37
CLCN2 P51788 1/20 0.37
HPGD P15428 1/20 0.36
AKR1B1 P15121 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10522348 0.80 GABRA1 (0.46) GABRA1GABRB2ALDH1A1MAPTPOLQ
SCHEMBL2964988 0.78 GABRA1 (0.45) GABRA1GABRB2CYP1A2ALDH1A1MAPT
SCHEMBL10448955 0.78 GABRA1 (0.45) GABRA1GABRB2ALDH1A1MAPTPOLQ
SCHEMBL10218791 0.78 GABRA1 (0.45) GABRA1GABRB2ALDH1A1MAPTPOLQ
SCHEMBL20592727 0.77 POLQ (0.44) GABRA1GABRB2ALDH1A1MAPTPOLQ
SCHEMBL7186121 0.76 CYP1A2 (0.43) GABRA1GABRB2CYP1A2ALDH1A1HPGD
SCHEMBL30335199 0.76 KCNN4 (0.44) GABRA1GABRB2CYP1A2ALDH1A1MAPT
Hydrogen Peroxide SCHEMBL11570368 0.75 GABRA1 (0.50) GABRA1GABRB2ALDH1A1MAPTKDM4E
SCHEMBL11872740 0.74 GABRA1 (0.40) GABRA1GABRB2CYP1A2ALDH1A1MAPT
SCHEMBL20564736 0.74 HIF1A (0.43) GABRA1GABRB2CYP1A2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020082368-A1 Novel vanadium catalyst system for EP(D)M slurry polymerisation BAYER POLYMERS LLC 2002-06-27 US claimed
EP-1203778-A1 Novel vanadium catalyst system for ep(d)m slurry polymerisation Bayer Inc. (CA) 2002-05-08 EP claimed
EP-0546629-B1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERS (IT) 1997-02-26 EP claimed
EP-0546629-A1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERI S.r.l. (IT) 1993-06-16 EP claimed
US-20030114596-A1 Thermoplastic elastomer composition and ethylene-alpha-olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-06-19 US disclosed
US-6541592-B1 An ethylene- alpha -olefin copolymer (alpha -olefin having 3 to 8 carbon atoms and content from 20-33.7wt %), Moony viscosity ML1+4100 degree C. of from 20-60, tensile stress M100 of 2.5 Mpa; excellent flexability, and processability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-01 US disclosed
US-20020082368-A1 Novel vanadium catalyst system for EP(D)M slurry polymerisation BAYER POLYMERS LLC 2002-06-27 US disclosed
EP-1203778-A1 Novel vanadium catalyst system for ep(d)m slurry polymerisation Bayer Inc. (CA) 2002-05-08 EP disclosed
EP-0660024-B1 Resin-coated pipe SUMITOMO CHEMICAL CO (JP) 1997-10-22 EP disclosed
EP-0546629-B1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERS (IT) 1997-02-26 EP disclosed
US-5571585-A HAVING EXCELLENT PROCESSABILITY, MECHANICAL STRENGTH, NORMAL AND LOW TEMPERATURE IMPACT RESISTANCE, HEAT RESISTANCE, CHIPPING RESISTANCE AND COATING SURFACE APPEEARANCE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-05 US disclosed
EP-0660024-A1 Resin-coated pipe SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-28 EP disclosed
EP-0362743-B1 Process for preparing ethylene homopolymers and copolymers of ethylene with higher alpha-olefins by means of a Ziegler catalytic system BASF AG (DE) 1994-02-02 EP disclosed
EP-0546629-A1 Process for preparing elastomeric copolymers of ethylene with a high tensile strength of the crude product ENICHEM ELASTOMERI S.r.l. (IT) 1993-06-16 EP disclosed
EP-0362744-A2 Process for preparing ethylene homopolymers and copolymers of ethylene with higher alpha-olefins by means of a Ziegler catalytic system BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0362743-A2 Process for preparing ethylene homopolymers and copolymers of ethylene with higher alpha-olefins by means of a Ziegler catalytic system BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0166888-B1 PROCESS FOR POLYMERIZING ETHYLENE OR COPOLYMERIZING ETHYLENE WITH HIGHER ALPHA-MONOOLEFINES WITH A ZIEGLER CATALYTIC SYSTEM BASF Aktiengesellschaft (DE) 1988-06-29 EP disclosed