SCHEMBL7186121

SCHEMBL7186121

Cc1ccccc1C(Cl)(Cl)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
HPGD P15428 5/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MYC P01106 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
ACHE P22303 1/20 0.36
CASR P41180 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21494916 0.82 CYP1A2 (0.42) CYP1A2HPGDGABRA1GABRB2NPC1
Acetic Acid SCHEMBL28614085 0.79 HPGD (0.39) CYP1A2HPGDGABRA1GABRB2NPC1
SCHEMBL11694364 0.79 CYP1A2 (0.64) CYP1A2HPGDGABRA1GABRB2GAA
SCHEMBL20563882 0.78 MYC (0.42) CYP1A2HPGDGABRA1GABRB2NPC1
SCHEMBL31503044 0.78 TSHR (0.39) CYP1A2HPGDGABRA1GABRB2NPC1
O-Xylene SCHEMBL28016180 0.78 ALDH1A1 (0.50) CYP1A2HPGDNPC1RAB9AGAA
Trichloroacetic Acid SCHEMBL5874544 0.77 KMT2A (0.39) CYP1A2HPGDGABRA1GABRB2GAA
SCHEMBL555423 0.77 HPGD (0.41) HPGDGABRA1GABRB2NPC1RAB9A
SCHEMBL3633862 0.77 GABRA1 (0.42) HPGDGABRA1GABRB2NPC1RAB9A
SCHEMBL4900842 0.77 KCNN4 (0.45) CYP1A2POLBTSHRALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606206-A Preparation process of picoxystrobin intermediate methyl o-chloromethyl phenylacetate 河北诚信集团有限公司 2023-08-18 CN disclosed
US-20030114596-A1 Thermoplastic elastomer composition and ethylene-alpha-olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-06-19 US disclosed
US-6541592-B1 An ethylene- alpha -olefin copolymer (alpha -olefin having 3 to 8 carbon atoms and content from 20-33.7wt %), Moony viscosity ML1+4100 degree C. of from 20-60, tensile stress M100 of 2.5 Mpa; excellent flexability, and processability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-01 US disclosed
EP-0660024-B1 Resin-coated pipe SUMITOMO CHEMICAL CO (JP) 1997-10-22 EP disclosed
US-5571585-A HAVING EXCELLENT PROCESSABILITY, MECHANICAL STRENGTH, NORMAL AND LOW TEMPERATURE IMPACT RESISTANCE, HEAT RESISTANCE, CHIPPING RESISTANCE AND COATING SURFACE APPEEARANCE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-05 US disclosed
EP-0660024-A1 Resin-coated pipe SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-28 EP disclosed
EP-0362743-B1 Process for preparing ethylene homopolymers and copolymers of ethylene with higher alpha-olefins by means of a Ziegler catalytic system BASF AG (DE) 1994-02-02 EP disclosed
US-5112928-A Coordination catalysts containing aluminum, vanadium and transition metal compounds BASF AKTIENGESELLSCHAFT (DE) 1992-05-12 US disclosed
EP-0362744-A2 Process for preparing ethylene homopolymers and copolymers of ethylene with higher alpha-olefins by means of a Ziegler catalytic system BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0362743-A2 Process for preparing ethylene homopolymers and copolymers of ethylene with higher alpha-olefins by means of a Ziegler catalytic system BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0166888-B1 PROCESS FOR POLYMERIZING ETHYLENE OR COPOLYMERIZING ETHYLENE WITH HIGHER ALPHA-MONOOLEFINES WITH A ZIEGLER CATALYTIC SYSTEM BASF Aktiengesellschaft (DE) 1988-06-29 EP disclosed