SCHEMBL7192042

SCHEMBL7192042

C[SiH](C)C1(OC(=O)c2ccc(C(=O)OC3([SiH](C)C)CCCCO3)cc2)CCCCO1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.36
GPR119 Q8TDV5 3/20 0.32
RARA P10276 3/20 0.32
RARB P10826 3/20 0.32
RARG P13631 3/20 0.32
RXRB P28702 4/20 0.32
CYP26A1 O43174 1/20 0.32
CYP26B1 Q9NR63 1/20 0.32
RXRG P48443 2/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
ALOX15 P16050 1/20 0.31
MGLL Q99685 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NPC1 O15118 3/20 0.30
RAB9A P51151 3/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7193282 0.90 NPSR1 (0.33) RXRAPOLBALDH1A1LMNASMN1; SMN2
SCHEMBL7190502 0.86 RAB9A (0.50) ALDH1A1HPGDHSD17B10NPC1RAB9A
SCHEMBL28637083 0.80
SCHEMBL7186028 0.80
SCHEMBL27474275 0.78
SCHEMBL440901 0.75 ALDH1A1 (0.31) ALDH1A1
SCHEMBL6447133 0.74
SCHEMBL2526679 0.74
SCHEMBL20554750 0.73
SCHEMBL27210119 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602609-B1 Multilayer polymeric film with non-migratory antiblock agent EXXONMOBIL OIL CORPORATION 2003-08-05 US claimed
WO-2001076868-A2 MULTILAYER POLYMERIC FILM WITH NON-MIGRATORY ANTIBLOCK AGENT MOBIL OIL CORPORATION (US) 2001-10-18 WO claimed
US-6602609-B1 Multilayer polymeric film with non-migratory antiblock agent EXXONMOBIL OIL CORPORATION 2003-08-05 US disclosed
WO-2001076868-A2 MULTILAYER POLYMERIC FILM WITH NON-MIGRATORY ANTIBLOCK AGENT MOBIL OIL CORPORATION (US) 2001-10-18 WO disclosed