Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447396 | 1.00 | LMNA (0.52) | LMNAMAPTSLC15A1CYP2D6MAPK1 | |
| SCHEMBL3071 | 1.00 | LMNA (0.52) | LMNAMAPTSLC15A1CYP2D6MAPK1 | |
| SCHEMBL7758366 | 0.91 | LMNA (0.51) | LMNAMAPTSLC15A1CYP2D6MAPK1 | |
| SCHEMBL716770 | 0.90 | LMNA (0.54) | LMNAMAPTCYP2D6MAPK1CA2 | |
| SCHEMBL1670578 | 0.90 | LMNA (0.54) | LMNAMAPTCYP2D6MAPK1CA2 | |
| SCHEMBL719791 | 0.90 | LMNA (0.54) | LMNAMAPTCYP2D6MAPK1CA2 | |
| SCHEMBL1287362 | 0.89 | LMNA (0.49) | LMNAMAPTSLC15A1CYP2D6MAPK1 | |
| SCHEMBL5917169 | 0.89 | LMNA (0.49) | LMNAMAPTSLC15A1CYP2D6MAPK1 | |
| SCHEMBL1287363 | 0.89 | LMNA (0.49) | LMNAMAPTSLC15A1CYP2D6MAPK1 | |
| SCHEMBL7759042 | 0.87 | LMNA (0.49) | LMNAMAPTCYP2D6MAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| US-8724296-B2 | Solid electrolytic capacitor and fabrication method thereof | SANYO ELECTRIC CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8425805-B2 | Conductive polymer film, electronic device, and methods of producing the film and the device | SANYO ELECTRIC CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20120049136-A1 | CONDUCTIVE POLYMER FILM, ELECTRIC DEVICES AND METHODS FOR MANUFACTURING THE CONDUCTIVE POLYMER FILM | SANYO ELECTRIC CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110051319-A1 | CONDUCTING POLYMER MEMBRANE, METHOD OF MANUFACTURING CONDUCTING POLYMER MEMBRANE, AND ELECTRONIC DEVICE | SANYO ELECTRIC CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20100271757-A1 | SOLID ELECTROLYTIC CAPACITOR AND FABRICATION METHOD THEREOF | SANYO ELECTRIC CO., LTD. (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20100232090-A1 | CONDUCTIVE POLYMER FILM, ELECTRONIC DEVICE, AND METHODS OF PRODUCING THE FILM AND THE DEVICE | SANYO ELECTRIC CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-6245938-B1 | COMPOUND SUITABLE FOR USE BOTH AS DERIVATIZING GROUP FOR OPTICAL SEPARATION OF ENANTIOMERS AND AS PROTECTING GROUP FOR PREPARATION OF MISACYLATED TRNA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-06-12 | — | — | US | disclosed |