SCHEMBL719307

SCHEMBL719307

CCCCCC(C)(C)c1c(C(C)(C)C)ccc2c1Nc1ccccc1S2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.37
GAA P10253 5/20 0.37
MAPT P10636 5/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALOX15 P16050 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
BCHE P06276 2/20 0.37
ACHE P22303 2/20 0.37
SNCA P37840 2/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
ALOX12 P18054 1/20 0.37
MAOA P21397 1/20 0.37
CNR1 P21554 1/20 0.37
PTGS1 P23219 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2C P28335 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44486 0.83 NOX1 (0.41) NOX1GAAMAPTMEN1KMT2A
SCHEMBL719308 0.83 NOX1 (0.41) NOX1GAAMAPTMEN1KMT2A
SCHEMBL5613284 0.82 GAA (0.35) NOX1GAAMAPTMEN1KMT2A
SCHEMBL2211992 0.80 NOX1 (0.41) NOX1GAAMAPTMEN1KMT2A
SCHEMBL29281324 0.79 NOX1 (0.42) NOX1GAAMAPTMEN1KMT2A
SCHEMBL5570560 0.78 NOX1 (0.41) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL28781231 0.72 NOX1 (0.71) NOX1GAAMAPTMEN1KMT2A
SCHEMBL9932693 0.72 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL3760150 0.69 NOX1 (0.43) NOX1GAAMAPTMEN1KMT2A
SCHEMBL9488587 0.69 NOX1 (0.50) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795414-B2 Metalworking fluid containing a branched alcohol propoxylate BASF SE 2023-10-24 US disclosed
US-20220162514-A1 METALWORKING FLUID CONTAINING A BRANCHED ALCOHOL PROPOXYLATE BASF SE (DE) 2022-05-26 US disclosed
EP-3953441-A1 METALWORKING FLUID CONTAINING A BRANCHED ALCOHOL PROPOXYLATE BASF SE (DE) 2022-02-16 EP disclosed
US-11161813-B2 Sterically hindered amines BASF SE (DE) 2021-11-02 US disclosed
WO-2020207881-A1 METALWORKING FLUID CONTAINING A BRANCHED ALCOHOL PROPOXYLATE BASF SE (DE) 2020-10-15 WO disclosed
US-20200123107-A1 STERICALLY HINDERED AMINES BASF SE (DE) 2020-04-23 US disclosed
EP-1730101-B1 ALKYLATED PANA AND DPA COMPOSITIONS BASF SE (DE) 2015-11-18 EP disclosed
US-9181481-B2 Liquid crystal display device and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-10 US disclosed
US-20150138493-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-05-21 US disclosed
US-20120051965-A1 N-ACYLSARCOSINE COMPOSITIONS BASF SE (DE) 2012-03-01 US disclosed
WO-2004104146-A1 BORATE ESTER LUBRICANT ADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-02 WO disclosed
EP-1451277-A1 AQUEOUS FUNCTIONAL FLUIDS WITH ANTIOXIDANTS Ciba SC Holding AG (CH) 2004-09-01 EP disclosed
WO-2004050671-A1 LIQUID PHENOLIC SULPHUR-CONTAINING ANTIOXIDANTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
US-20040110876-A1 Stabilizers for powder coatings LAVER HUGH STEPHEN (CH) 2004-06-10 US disclosed
US-20040063830-A1 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORPORATION 2004-04-01 US disclosed
WO-2003044140-A1 AQUEOUS FUNCTIONAL FLUIDS WITH ANTIOXIDANTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
WO-2003004476-A1 AMINOALKYL-SUBSTITUTED BENZOTRIAZOLES AND TRIAZOLES AS METAL DEACTIVATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-01-16 WO disclosed
US-6403680-B1 PHOTO, HEAT, OXIDATION STABILIZERS CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-11 US disclosed
US-6365653-B1 SUITABLE AS COLOUR-STABLE AND NONSTAINING STABILIZERS AND ANTIOZONANTS FOR PROTECTING NONBLACK ELASTOMERS AGAINST OXIDATIVE, THERMAL, LIGHT- OR OZONE-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
US-20020016266-A1 Lubricant compositions comprising thiophosphoric acid esters and dithiophosphoric acid esters FLETSCHINGER MICHAEL (DE) 2002-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161813-B2 Sterically hindered amines H1-0, F12, H1-2 NOX1 84/4885GAA 3191/4885MAPT 1749/4885
US-20200123107-A1 STERICALLY HINDERED AMINES H1-0, F12, H1-2 NOX1 84/4885GAA 3191/4885MAPT 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.