SCHEMBL9932693

SCHEMBL9932693

CC(C)(C)c1cccc2c1Nc1ccccc1S2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.53
MAPT P10636 7/20 0.53
GAA P10253 6/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
ALOX15 P16050 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
BCHE P06276 2/20 0.53
ACHE P22303 2/20 0.53
SNCA P37840 2/20 0.53
CYP1A2 P05177 2/20 0.53
POLB P06746 1/20 0.53
CYP3A4 P08684 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
ALOX12 P18054 1/20 0.53
MAOA P21397 1/20 0.53
CNR1 P21554 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
HTR2C P28335 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628202 0.87 CA2 (0.41) NOX1MAPTGAAMEN1KMT2A
SCHEMBL29636472 0.87 CA2 (0.41) NOX1MAPTGAAMEN1KMT2A
SCHEMBL1720021 0.84 NOX1 (0.47) NOX1MAPTGAAMEN1KMT2A
SCHEMBL29421160 0.83 NOX1 (0.46) NOX1MAPTGAAMEN1KMT2A
SCHEMBL44485 0.83 NOX1 (0.46) NOX1MAPTGAAMEN1KMT2A
SCHEMBL28796458 0.83 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL1080885 0.83 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL29029462 0.82 NOX1 (0.44) NOX1MAPTGAAMEN1KMT2A
Hydrochloric Acid SCHEMBL2228440 0.81 NOX1 (0.52) NOX1MAPTGAAMEN1KMT2A
Iodide SCHEMBL9932580 0.80 NOX1 (0.50) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513238-A Stable compositions comprising leuco compounds 美利肯公司 2021-03-16 CN claimed
US-10233298-B2 Polyurethane foams based on polyether carbonate polyols COVESTRO DEUTSCHLAND AG (DE) 2019-03-19 US claimed
CN-118234793-A Stabilizer based on syringic acid, vanillic acid, isovanillic acid or 5-hydroxyveratric acid, plastic composition, method for stabilizing a plastic composition and stabilizer composition 弗劳恩霍夫应用研究促进协会 2024-06-21 CN disclosed
CN-113166467-B Polyethylene or polypropylene articles 巴斯夫欧洲公司 2024-03-29 CN disclosed
CN-117529306-A Nicotinamide Adenine Dinucleotide (NAD) compositions, methods of making and methods of using the same 索维达解决方案有限公司 2024-02-06 CN disclosed
CN-117479945-A Large conductance potassium channel modulators, compositions thereof, methods of making and methods of using the same 依那拉治疗股份有限公司 2024-01-30 CN disclosed
CN-117203272-A Stabilizer mixture 巴斯夫欧洲公司 2023-12-08 CN disclosed
CN-116211020-A Footwear sole structure with composite elements and method for making the same 耐克创新有限合伙公司 2023-06-06 CN disclosed
CN-116144066-A Method for producing thermoplastic foam articles 耐克创新有限合伙公司 2023-05-23 CN disclosed
CN-116138540-A Two-part sole structure and use thereof 耐克创新有限合伙公司 2023-05-23 CN disclosed
CN-116120721-A Thermoplastic foam article 耐克创新有限合伙公司 2023-05-16 CN disclosed
CN-110809600-A Polyethylene pipe 巴斯夫欧洲公司 2020-02-18 CN disclosed
CN-110678097-A Method for manufacturing articles using foam particles 耐克创新有限合伙公司 2020-01-10 CN disclosed
CN-110678510-A Nucleating agents, methods of making the same and related polymer compositions 巴斯夫欧洲公司 2020-01-10 CN disclosed
EP-2699241-B1 ANTIVIRAL COMPOUNDS PROSETTA ANTIVIRAL INC (US) 2016-07-27 EP disclosed
EP-2585073-B1 ANTIVIRAL COMPOUNDS PROSETTA ANTIVIRAL INC (US) 2016-04-27 EP disclosed
US-8828986-B2 Antiviral compounds PROSETTA ANTIVIRAL INC. (US) 2014-09-09 US disclosed
US-8785434-B2 Antiviral compounds PROSETTA ANTIVIRAL INC. (US) 2014-07-22 US disclosed
US-20120270854-A1 Antiviral Compounds PROSETTA ANTIVIRAL INC. (US) 2012-10-25 US disclosed
US-20120157435-A1 Antiviral Compounds PROSETTA ANTIVIRAL INC. (US) 2012-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157435-A1 Antiviral Compounds MAVS, ZC3HAV1, EIF2AK2 NOX1 2140/4885MAPT 693/4885GAA 254/4885
US-20120270854-A1 Antiviral Compounds HAVCR2, MAVS, EIF2AK2 NOX1 2733/4885MAPT 1569/4885GAA 191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.