Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197851 | 0.85 | DHODH (0.40) | DHODH | |
| SCHEMBL7200557 | 0.85 | DHODH (0.42) | ALDH1A1HPGDDHODHCYP1A2SMN1; SMN2 | |
| SCHEMBL7197499 | 0.72 | DHODH (0.55) | DHODH | |
| SCHEMBL7193533 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TDP1MAPTNPC1HPGD | |
| SCHEMBL16920917 | 0.67 | SLC22A12 (0.53) | ALDH1A1MAPTHPGDRAB9ACYP3A4 | |
| SCHEMBL3141899 | 0.66 | MRGPRX4 (0.51) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL16920916 | 0.65 | MRGPRX4 (0.60) | NPC1RAB9A | |
| SCHEMBL18831484 | 0.65 | MRGPRX4 (0.50) | ALDH1A1HPGD | |
| SCHEMBL7133454 | 0.65 | TSHR (0.44) | ALDH1A1TDP1MAPTLMNA | |
| SCHEMBL17788227 | 0.65 | SLC22A12 (0.50) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |