SCHEMBL7197851

SCHEMBL7197851

CCc1nc2c(C)cc(OCc3c(C)cccc3C(=O)O)cc2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 13/20 0.40
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200557 0.88 DHODH (0.42) DHODH
SCHEMBL7193541 0.85 ALDH1A1 (0.46) DHODH
SCHEMBL6501625 0.78 PTGES (0.40) DHODH
SCHEMBL9413571 0.75 PRKCZ (0.40)
SCHEMBL7197499 0.74 DHODH (0.55) DHODH
SCHEMBL15808131 0.71 KDM4E (0.56) DHODH
SCHEMBL6491891 0.70 PDE3B (0.48)
SCHEMBL8847752 0.70 PRKCZ (0.42)
SCHEMBL16920917 0.69 SLC22A12 (0.53)
SCHEMBL3141899 0.68 MRGPRX4 (0.51) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004108686-A2 BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-12-16 WO disclosed