Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720413 | 1.00 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL719369 | 1.00 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL119041 | 0.89 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL718935 | 0.87 | MEP1B (0.36) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL720863 | 0.87 | MEP1B (0.36) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL718934 | 0.87 | MEP1B (0.36) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL116281 | 0.86 | KDM4E (0.36) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10252352 | 0.85 | KDM4E (0.35) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL721102 | 0.83 | KDM4E (0.35) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL718750 | 0.81 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | KDM4E 2202/4885PKM 1703/4885RCE1 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.