Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.31 |
| ▸ | DHPS | P49366 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252352 | 0.90 | KDM4E (0.35) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1223276 | 0.89 | TDP1 (0.33) | KDM4ESCN10A | |
| SCHEMBL721102 | 0.88 | KDM4E (0.35) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14478775 | 0.87 | KDM4E (0.32) | KDM4EPKMALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1478316 | 0.87 | KDM4E (0.39) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL119041 | 0.86 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL718750 | 0.86 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL719370 | 0.86 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL719369 | 0.86 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL720147 | 0.86 | MEN1 (0.34) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199943-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9199943-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9199943-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-20130237422-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130237422-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130237422-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130005577-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130005577-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130005577-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-01-03 | — | — | US | disclosed |
| US-8288318-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2012-10-16 | — | — | US | disclosed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
| EP-1971579-B1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20090149329-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (IN) | 2009-06-11 | — | — | US | disclosed |
| US-7538214-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1971579-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2008-09-24 | — | — | EP | disclosed |
| US-20080091016-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-04-17 | — | — | US | disclosed |
| US-7300907-B2 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070179059-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007082076-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149329-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DDT, DDC, HDHD5 | KDM4E 567/4885PKM 2577/4885RCE1 2426/4885 |
| US-20130237422-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DDT, DDC, HDHD5 | KDM4E 567/4885PKM 2577/4885RCE1 2426/4885 |
| US-20080091016-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DDT, DDC, HDHD5 | KDM4E 567/4885PKM 2577/4885RCE1 2426/4885 |
| US-20130005577-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DDT, DDC, HDHD5 | KDM4E 567/4885PKM 2577/4885RCE1 2426/4885 |
| US-20070179059-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DDT, DDC, HDHD5 | KDM4E 567/4885PKM 2577/4885RCE1 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.