SCHEMBL7194152

SCHEMBL7194152

Cc1ccc2cc(C(=O)OCCO)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.49
HRH3 Q9Y5N1 2/20 0.47
DRD3 P35462 1/20 0.45
RAB9A P51151 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPC1 O15118 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CYP1A2 P05177 1/20 0.42
SLC7A5 Q01650 1/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465188 0.90 HRH3 (0.50) HRH3DRD3TDP1CA12CA1
SCHEMBL9814333 0.85 PTPN11 (0.53) HRH3DRD3RAB9ACA12CA1
SCHEMBL11983376 0.85 CA12 (0.59) CYP2A6RAB9ATDP1L3MBTL1CA12
SCHEMBL14707366 0.85 HRH3 (0.50) HRH3DRD3TDP1SLC7A5KDM4E
SCHEMBL16606218 0.83 HRH3 (0.59) HRH3DRD3RAB9ATDP1NPC1
SCHEMBL7156008 0.83 KDM4E (0.50) HRH3DRD3TDP1SLC7A5KDM4E
SCHEMBL30741570 0.83 KDM4E (0.50) HRH3DRD3TDP1SLC7A5KDM4E
SCHEMBL1614890 0.83 TDP1 (0.55) RAB9ATDP1NPC1CA12CA1
SCHEMBL24523139 0.82 HRH3 (0.60) CYP2A6HRH3DRD3RAB9ATDP1
SCHEMBL13698260 0.81 SLC7A5 (0.45) HRH3DRD3RAB9ATDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642407-B2 Esterifying the crude aryldicarboxylic acid with an alcohol, removing volatile impurities from the esterification effluent by distillation and separating the aryldicarboxylic acid ester from said effluent EXXON MOBIL CHEMICAL PATENTS INC. 2003-11-04 US disclosed
WO-2002094757-A1 PRODUCTION, PURIFICATION AND POLYMERIZATION OF DICARBOXYLIC ACIDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-11-28 WO disclosed
US-20020173674-A1 Production, purification and polymerization of aromatic dicarboxylic acids EXXONMOBIL CHEMICAL PATENTS, INC. 2002-11-21 US disclosed
US-20020173673-A1 Production, purification and polymerization of aromatic dicarboxylic acids EXXONMOBIL CHEMICAL PATENTS, INC. 2002-11-21 US disclosed