SCHEMBL1614890

SCHEMBL1614890

Cc1ccc(C(=O)OCCO)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.55
RAB9A P51151 4/20 0.54
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 2/20 0.54
MAPT P10636 1/20 0.54
ESR1 P03372 3/20 0.52
TSHR P16473 3/20 0.52
CHRM1 P11229 1/20 0.52
SLC6A2 P23975 1/20 0.52
KDR P35968 1/20 0.52
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ESR2 Q92731 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ADRB2 P07550 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14231643 0.94 RAB9A (0.50) TDP1RAB9AALDH1A1NPC1MAPT
P-Xylene SCHEMBL28358132 0.93 ALDH1A1 (0.59) TDP1RAB9AALDH1A1NPC1MAPT
Ethylene Glycol SCHEMBL3446601 0.92 TDP1 (0.55) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL206554 0.90 TDP1 (0.61) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL26378 0.89 TDP1 (0.56) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL16900467 0.89 RAB9A (0.49) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL28228923 0.89 RAB9A (0.49) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL11593251 0.88 CA1 (0.66) TDP1RAB9AALDH1A1NPC1MAPT
Acetone SCHEMBL28904622 0.88 TSHR (0.55) TDP1RAB9AALDH1A1NPC1MAPT
Lithium SCHEMBL30805733 0.87 TDP1 (0.54) TDP1RAB9AALDH1A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910532-B1 USE OF ESTERASES FOR SEPARATING PLASTICS HENKEL AG & CO KGAA (DE) 2011-07-20 EP claimed
US-12031128-B2 Rapid design, build, test, and learn technologies for identifying and using non-viral carriers BATTELLE MEMORIAL INSTITUTE (US) 2024-07-09 US disclosed
US-12031128-B2 Rapid design, build, test, and learn technologies for identifying and using non-viral carriers BATTELLE MEMORIAL INSTITUTE (US) 2024-07-09 US disclosed
CN-112135598-B Macromer-based photocurable dental impression material 登士柏希罗纳有限公司 2023-12-22 CN disclosed
US-20220175812-A1 POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY BATTELLE MEMORIAL INSTITUTE 2022-06-09 US disclosed
WO-2022120194-A1 POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY BATTELLE MEMORIAL INSTITUTE (US) 2022-06-09 WO disclosed
US-10475546-B2 Conductors comprising a functionalized organosiloxane network and methods for the preparation thereof NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2019-11-12 US disclosed
US-10295882-B2 Display device NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) 2019-05-21 US disclosed
US-9487631-B2 Surface active polymeric systems UNIVERSITY OF DURHAM (GB) 2016-11-08 US disclosed
US-8846070-B2 Biologically degradable compositions for medical applications ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2014-09-30 US disclosed
US-20090286098-A1 Optical Film, Method of Producing the Same and Image Displaying Apparatus Employing the Optical Film KONICA MINOLTA OPTO, INC. (JP) 2009-11-19 US disclosed
US-20090258406-A1 Use of esterases for separating plastics HENKEL KGAA (DE) 2009-10-15 US disclosed
US-20090135345-A1 Polarizing Plate Protective Film, Film Producing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-05-28 US disclosed
US-7229987-B2 Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes ELI LILLY AND COMPANY (US) 2007-06-12 US disclosed
US-7229987-B2 Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes ELI LILLY AND COMPANY (US) 2007-06-12 US disclosed
US-20070046872-A1 Liquid crystal display KONICA MINOLTA OPTO, INC. 2007-03-01 US disclosed
US-20060280882-A1 Cellulose ester film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2006-12-14 US disclosed
US-20060202366-A1 Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. 2006-09-14 US disclosed
US-20060078754-A1 Optical film, polarizing plate and display KONICA MINOLTA OPTO, INC. (JP) 2006-04-13 US disclosed
US-20060060997-A1 Polarizing plate protective film and manufacturing method for the same KONICA MINOLTA OPTO, INC. 2006-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12031128-B2 Rapid design, build, test, and learn technologies for identifying and using non-viral carriers PHAX, POLRMT, RFTN1 TDP1 158/4885RAB9A 2708/4885ALDH1A1 3308/4885
US-20220175812-A1 POLYMER NANOPARTICLE AND DNA NANOSTRUCTURE COMPOSITIONS AND METHODS FOR NON-VIRAL DELIVERY POLN, POLRMT, MAVS TDP1 260/4885RAB9A 2730/4885ALDH1A1 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.