SCHEMBL7194341

SCHEMBL7194341

CCCCOC(=O)c1cccnc1C(c1ccc(N(C)C)cc1C)c1c(C)n(CC)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
KDM4A O75164 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
TSHR P16473 7/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 7/20 0.35
GAA P10253 2/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALOX15 P16050 1/20 0.35
ATM Q13315 1/20 0.35
CNR2 P34972 3/20 0.34
CYP3A4 P08684 3/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7185303 0.90 PTGER4 (0.36) KDM4ETSHRL3MBTL1ALDH1A1GAA
SCHEMBL7193177 0.89 TSHR (0.39) KDM4ETSHRL3MBTL1TDP1ALDH1A1
SCHEMBL7191366 0.86 KDM4E (0.40) KDM4ETSHRL3MBTL1ALDH1A1GAA
SCHEMBL7188094 0.83 SMN1; SMN2 (0.36) KDM4EL3MBTL1ALDH1A1HSD17B10ALOX15
SCHEMBL7194548 0.82 MAPT (0.35) KDM4EALDH1A1HPGDCYP3A4MAPT
SCHEMBL7187904 0.78 NR4A2 (0.38) KDM4ETSHRL3MBTL1ALDH1A1GAA
SCHEMBL7189604 0.74 GABRP (0.37) KDM4EALDH1A1GAAHPGDMAPT
SCHEMBL10693188 0.72 ALDH1A1 (0.39) KDM4ETDP1ALDH1A1GAAHPGD
SCHEMBL7181782 0.71 MAPT (0.38) KDM4ETSHRL3MBTL1ALDH1A1GAA
SCHEMBL7193629 0.70 KDM4E (0.38) KDM4EALDH1A1HPGDATMCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586364-B2 Shell walls; liquid coloring PENTAX CORPORATION (JP) 2003-07-01 US disclosed
US-20020168580-A1 Heat-sensitive microcapsule and recording medium using same ASAHI KOGAKU KOGYO KABUSHIKI KAISHA 2002-11-14 US disclosed