Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719700 | 0.98 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL717011 | 0.96 | GCG (0.35) | ALDH1A1KDM4EGCGNPC1RAB9A | |
| SCHEMBL724281 | 0.90 | GPR132 (0.37) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL721587 | 0.90 | KDM4E (0.35) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL718844 | 0.89 | KDM4E (0.38) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL716997 | 0.88 | GCG (0.44) | ALDH1A1KDM4EGCGKMT2AMEN1 | |
| SCHEMBL720179 | 0.88 | MAPK14 (0.37) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL718846 | 0.88 | KDM4E (0.36) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL724867 | 0.87 | MEN1 (0.42) | ALDH1A1KDM4EHPGDTSHRMAPK1 | |
| SCHEMBL719699 | 0.86 | KDM4E (0.34) | ALDH1A1KDM4EHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | ALDH1A1 504/4885KDM4E 1907/4885HPGD 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.