Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20935052 | 1.00 | HTT (0.67) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7194878 | 1.00 | HTT (0.67) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29387003 | 0.94 | HTT (0.59) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7195875 | 0.88 | HTT (0.65) | HTTHPGDLMNAALDH1A1GAA | |
| SCHEMBL7195870 | 0.88 | HTT (0.65) | HTTHPGDLMNAALDH1A1GAA | |
| SCHEMBL7202487 | 0.87 | HTT (0.52) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7202483 | 0.87 | HTT (0.52) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22550043 | 0.83 | HTT (0.47) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28637934 | 0.81 | MAPT (0.49) | HTTHPGDLMNAALDH1A1GAA | |
| SCHEMBL11372119 | 0.80 | HTT (1.00) | HTTLMNAL3MBTL1ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596445-B1 | Initiators for photopolymerization of radically polymerizable compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |