Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202487 | 1.00 | HTT (0.52) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL20935415 | 0.94 | LMNA (0.44) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL14429955 | 0.89 | HPGD (0.50) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL20935052 | 0.87 | HTT (0.67) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7194873 | 0.87 | HTT (0.67) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7194878 | 0.87 | HTT (0.67) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1478455 | 0.85 | HTT (0.42) | HTTLMNAALDH1A1PKMKMT2A | |
| SCHEMBL1478456 | 0.85 | HTT (0.42) | HTTLMNAALDH1A1PKMKMT2A | |
| SCHEMBL29387003 | 0.81 | HTT (0.59) | HTTHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL20709714 | 0.81 | CYP3A4 (0.36) | HTTHPGDLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596445-B1 | Initiators for photopolymerization of radically polymerizable compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |