SCHEMBL7195074

SCHEMBL7195074

Oc1nc2ncccn2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
ALDH1A1 P00352 3/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.40
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
PIK3CG P48736 1/20 0.36
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
USP2 O75604 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 2/20 0.35
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CDK2 P24941 1/20 0.34
ROCK2 O75116 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2668952 0.77 PDE10A (0.47) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL10921639 0.75 PDE10A (0.45) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL21389568 0.75 PDE10A (0.45) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL9933090 0.75 PDE10A (0.45) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL12989975 0.75 PDE10A (0.45) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL858832 0.75 MAP4K4 (0.46) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL259293 0.75 PDE10A (0.45) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL14629340 0.75 PIK3CG (0.44) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL4473144 0.75 NPC1 (0.45) PDE10ANPC1RAB9AALDH1A1TSHR
SCHEMBL4158096 0.73 MEN1 (0.57) PDE10ANPC1RAB9AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208346-A2 Diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1987-01-14 EP claimed
JP-62055644-A None JP disclosed
US-6593071-B2 Sensitivity reduction and deterioration in image quality, due to radiation KONICA CORPORATION (JP) 2003-07-15 US disclosed
US-20020061478-A1 Silver halide photographic emulsion and silver halide photographic light sensitive material KONICA CORPORATION, A CORP. OF JAPAN (JP) 2002-05-23 US disclosed
EP-0393721-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0393711-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0391405-A2 Silver halide photographic material and method for processing thereof FUJI PHOTO FILM CO., LTD. (JP) 1990-10-10 EP disclosed
JP-S6255644-A SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL KONISHIROKU PHOTO IND CO LTD 1987-03-11 JP disclosed
EP-0208346-A2 Diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1987-01-14 EP disclosed
EP-0023661-A2 Photographic silver halide emulsion with a stabilizer, process for its production, photographic recording materials and method of making photographic images Agfa-Gevaert AG (DE) 1981-02-11 EP disclosed