Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195147 | 1.00 | APLNR (0.50) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL30364356 | 0.94 | APLNR (0.48) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL31683847 | 0.90 | C5AR1 (0.44) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL29607931 | 0.89 | C5AR1 (0.55) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL31683844 | 0.87 | APLNR (0.46) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL29630628 | 0.87 | APLNR (0.49) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL29608840 | 0.87 | C5AR1 (0.58) | APLNRC5AR1MC4ROPRM1OPRK1 | |
| SCHEMBL29608843 | 0.87 | C5AR1 (0.58) | APLNRC5AR1MC4ROPRM1OPRK1 | |
| SCHEMBL29607221 | 0.86 | C5AR1 (0.53) | APLNRC5AR1CTSLCTSSCTSK | |
| SCHEMBL29591975 | 0.86 | APLNR (0.51) | APLNRC5AR1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589937-B1 | Anti-dementia drug which contains one or more of these new peptides and has a high blood brain barrier (BBB) permeability and furthermore is low in a side effect. | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-0919567-B1 | NOVEL PEPTIDES AND NOOTROPIC AGENT | YAKULT HONSHA KK (JP) | 2001-10-24 | — | — | EP | disclosed |
| EP-0919567-A1 | NOVEL PEPTIDES AND NOOTROPIC AGENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1999-06-02 | — | — | EP | disclosed |