Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29651804 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP19A1HTR2A | |
| Iodide SCHEMBL27933233 | 0.96 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1HTR2A | |
| Bromide SCHEMBL27933221 | 0.96 | HTR2A (0.34) | CYP11B1CYP11B2CYP19A1HTR2A | |
| Fluoride Ion SCHEMBL27933167 | 0.96 | CYP11B1 (0.34) | CYP11B1CYP11B2CYP19A1HTR2A | |
| Hydrochloric Acid SCHEMBL27459244 | 0.95 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL812474 | 0.85 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL813276 | 0.82 | CYP3A4 (0.36) | CYP11B1CYP11B2 | |
| Bromide SCHEMBL27203208 | 0.81 | HTR2A (0.32) | CYP11B1CYP11B2HTR2A | |
| Iodide SCHEMBL27932942 | 0.81 | CYP3A4 (0.32) | CYP11B1CYP11B2 | |
| Fluoride Ion SCHEMBL27948626 | 0.81 | CYP3A4 (0.32) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104558340-A | Propylene polymer with polar groups and preparation method of propylene polymer | CHINA PETROLEUM & CHEMICAL | 2015-04-29 | — | — | CN | claimed |
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | claimed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | claimed |
| US-5145819-A | 2-SUBSTITUTED DISINDENYLMETALLOCENES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS CATALYSTS IN THE POLYMERIZATION OF OLEFINS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | claimed |
| CN-116199813-A | Long chain branched polypropylene and preparation method thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-115141298-A | Polyolefin resin and process for producing the same | DL化学株式会社 | 2022-10-04 | — | — | CN | disclosed |
| CN-111454389-B | Catalyst composition for polymerization of polyolefin, method for preparing polyolefin, and polyolefin resin | DL化学株式会社 | 2022-07-15 | — | — | CN | disclosed |
| CN-111454389-A | Catalyst composition for polymerization of polyolefin, process for producing polyolefin, and polyolefin resin | 大林产业株式会社 | 2020-07-28 | — | — | CN | disclosed |
| CN-110483670-A | The method of metallocene complex and production olefin polymer | JAPAN POLYPROPYLENE CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-106132975-B | Metallocene complex and process for producing olefin polymer | 日本聚丙烯株式会社 | 2019-11-08 | — | — | CN | disclosed |
| CN-103509060-B | Metallocene compound, the carbon monoxide-olefin polymeric comprising metallocene compound and the olefine polymerizing process of use metallocene compound | 大林产业株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-103012623-B | Metalloscene catalyst, its synthesis and purposes in olefin polymerization | NOVOLEN TECH HOLDINGS CV (DE) | 2015-09-16 | — | — | CN | disclosed |
| EP-0882054-A1 | LIQUID CLATHRATE ALUMINOXANE COMPOSITIONS | ALBEMARLE CORPORATION (US) | 1998-12-09 | — | — | EP | disclosed |
| CN-1175588-A | Polyolefine moulding materials for mfg. fibre net | HOECHST AG (DE) | 1998-03-11 | — | — | CN | disclosed |
| CN-1160055-A | Process for reducing by-product in product mixture | HOECHST AG (DE) | 1997-09-24 | — | — | CN | disclosed |
| WO-1997014700-A1 | LIQUID CLATHRATE ALUMINOXANE COMPOSITIONS | ALBEMARLE CORPORATION (US) | 1997-04-24 | — | — | WO | disclosed |
| CN-1123796-A | Process for the preparation of amorphous propylene polymers | SPHERILENE SPA (IT) | 1996-06-05 | — | — | CN | disclosed |
| CN-1107854-A | Metalocenes compound | HOECHST AG (DE) | 1995-09-06 | — | — | CN | disclosed |
| CN-1107162-A | Metallocen method for preparation of same and application of same as catalyst | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| US-5346925-A | Method for producing α-olefin polymers | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1994-09-13 | — | — | US | disclosed |