Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29230327 | 0.77 | KDM4E (0.38) | ALDH1A1HDAC1HDAC6NOS3NOS2 | |
| SCHEMBL30945122 | 0.77 | KDM4E (0.38) | ALDH1A1HDAC1HDAC6NOS3NOS2 | |
| SCHEMBL30945119 | 0.77 | KDM4E (0.38) | ALDH1A1HDAC1HDAC6NOS3NOS2 | |
| SCHEMBL27833168 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL27753989 | 0.76 | GAA (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4EMEN1 | |
| SCHEMBL27710395 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HDAC1HDAC6LMNALIMK1 | |
| SCHEMBL5460611 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL82306 | 0.75 | LMNA (0.43) | ALDH1A1HDAC1HDAC6SMN1; SMN2LMNA | |
| SCHEMBL31003562 | 0.75 | LMNA (0.43) | ALDH1A1HDAC1HDAC6SMN1; SMN2LMNA | |
| SCHEMBL12922670 | 0.75 | KCNQ3 (0.42) | ALDH1A1LMNAMEN1KMT2ALIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586452-B1 | Plant extracts used as miticides, parasiticides, insecticides and/or anthelmintics | MERCK & CO., INC. | 2003-07-01 | — | — | US | disclosed |